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ETHYLTHIOUREA

ETHYLTHIOUREA ??? ???
?? ??:
625-53-6
???:
ETHYLTHIOUREA
???(??):
N-ETHYLTHIOUREA;Nsc62921;Ent 61326;ETHYLTHIOUREA;1-ETHYLTHIOUREA;ethyl-2-thiourea;Thiourea, ethyl-;Ethylthiourea,99%;1-ETHYL-2-THIOUREA;1-ethyl-2-thio-ure
CBNumber:
CB6416447
???:
C3H8N2S
??? ??:
104.17
MOL ??:
625-53-6.mol
MSDS ??:
SDS

ETHYLTHIOUREA ??

???
108-110 °C(lit.)
?? ?
132 °C
??
1.055 (estimate)
???
1.5500 (estimate)
?? ??
Store at RT
???
???: ???25mg/mL, ??, ??
??? ??
??
??? ??
??? ??
?? ?? (pKa)
14.97±0.29(Predicted)
??
???? ?????
???
?? ???(24g/L).
BRN
1699551
InChIKey
GMEHFXXZSWDEDB-UHFFFAOYSA-N
CAS ??????
625-53-6(CAS DataBase Reference)
EPA
Ethylthiourea (625-53-6)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T
?? ???? ?? 25
????? 36/37/39-45
????(UN No.) UN 2811 6.1/PG 3
WGK ?? 3
RTECS ?? YT3700000
TSCA Yes
?? ?? 6.1
???? III
?? ?? ??? 625-53-6(Hazardous Substances Data)
?? mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981.
????(GHS): GHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H301 ??? ??? ?? ?? ?? - ?? ?? 3 ?? GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
??????:
NFPA 704
1
3 0

ETHYLTHIOUREA C??? ??, ??, ??

??

N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides

?? ??

N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.

???? ??

Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).

Safety Profile

Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.

Purification Methods

Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]

ETHYLTHIOUREA ?? ?? ? ???

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ETHYLTHIOUREA ?? ??

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