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65-31-6
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???(??):
????????;?????;????????;??? ?????;(-)-??? ???????;(-)-??? ?? (+)-?????;3-[(2S)-1-??-2-?????]???, (2R,3R)-2,3-???????????????? (1:2);??? ???????;??? ???????;??? ?? ?????;??? ??;??? ??? ???????;???? ?????;??????????
???:
Nicotine ditartrate
???(??):
NICOTINE BITARTRATE;Salt Nicotine;NicotinbitartrateDihydrate;nikotinbitartrat;NICOTINE TARTRATE;tartratedenicotine;Nicotine Difartrate;nicotineacidtartrate;nicotine,tartrate(1:2);(-)-Nicotine ditatrate
CBNumber:
CB6403397
???:
C18H26N2O12
??? ??:
462.41
MOL ??:
65-31-6.mol
MSDS ??:
SDS

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???
90°
??
D20 +26° (c = 10)
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Desiccate at RT
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H2O: 50 mg/mL
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optical activity
[α]/D +20 to +26°, c = 1.0 in water
InChIKey
RFEJUZJILGIRHQ-UHFFFAOYSA-N
CAS ??????
65-31-6(CAS DataBase Reference)
EPA
Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2) (65-31-6)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T+,N
?? ???? ?? 26/27/28-51/53
????? 13-28-45-61
????(UN No.) UN 1659 6.1/PG 2
WGK ?? 2
RTECS ?? QT0350000
?? ?? 6.1(a)
???? II
?? ?? ??? 65-31-6(Hazardous Substances Data)
???? ?? KE-25881
?????? ??? 97-1-11
?? ? ???? ????: ????; ???(??)????: ???? ? ?? ? ? ? ??? 1% ?? ??? ???
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H411 ??? ??? ?? ????? ??? ?? ????? ?? - ?? ?? 2
??????:
P260 ??·?·??·???·??·...·????? ???? ???.
P262 ?, ??, ??? ?? ??? ???.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
NFPA 704
0
2 0

??? ????? MSDS


3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate

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nicotinyl acetylchloline receptor agonist, ectoparasiticide

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Potent agonist of the nicotinic acetylcholine receptor. Stimulates autonomic ganglia and skeletal muscle neuromuscular junctions.

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Nicotinic acetylcholine receptor (nAChR) agonist (K i values are 1, > 1000, 4000 and 7130 nM at α 4 β 2, α 1 β 1 δ γ , rat α 7 and human α 7 respectively). Exhibits vasoconstrictive, hypertensive and prothrombotic activity in vivo .

Safety Profile

Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and CO. See also NICOTINE.

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