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124-76-5
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DL-Isoborneol
???(??):
ISOBORNEOL;Borneolum;exo-Borneol;Isobornyl alcohol;1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol;rel-(1R,2R,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol;FEMA 2158;Exoborneol;Isocamphol;( )-borneol
CBNumber:
CB6376754
???:
C10H18O
??? ??:
154.25
MOL ??:
124-76-5.mol
MSDS ??:
SDS

?????? ??

???
212-214 °C (subl.)(lit.)
?? ?
214°C
??
0.8389 (rough estimate)
???
0.057-4.706Pa at 25℃
FEMA
2158 | ISOBORNEOL
???
1.4710 (estimate)
???
200 °F
?? ??
2-8°C
???
almost transparency in Methanol
??? ??
??
?? ?? (pKa)
15.36±0.60(Predicted)
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???
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????? ??? ? 10.00%. ?? ?? ?? ??
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???
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synthetic
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Merck
14,5128
JECFA Number
1386
BRN
4126091
LogP
2.32-2.92 at 20-25℃
CAS ??????
124-76-5(CAS DataBase Reference)
NIST
DL-Isoborneol(124-76-5)
EPA
Isoborneol (124-76-5)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? F,Xi
?? ???? ?? 11-38
????? 24/25
????(UN No.) UN 1312 4.1/PG 3
WGK ?? 2
RTECS ?? NP7300000
TSCA Yes
?? ?? 4.1
HS ?? 29061900
?? ?? ??? 124-76-5(Hazardous Substances Data)
?? mouse,LD50,intravenous,56mg/kg (56mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03209,
???? ?? KE-34419
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H228 ??? ?? ??? ?? ?? 1
?? 2
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GHS hazard pictograms P210, P240,P241, P280, P370+P378
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
??????:
P210 ?·???·??·????? ????? - ?? ???.
P302+P352 ??? ??? ??? ?? ????.
NFPA 704
1 0

?????? MSDS


1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

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Isoborneol has a piney, camphoraceous odor. May be prepared by the hydrolysis of isobomyl acetate, or by catalytic reduction of camphor (both d- and ι-isomers); the optically inactive compound can be prepared by treating camphene with a 1:1 mixture of sulfuric acid and glacial acetic acid and then hydrolyzing the isobomyl acetat.

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white to almost white crystalline powder

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Reported found in the oil of Abies sibirica and a few other essences and in the essential oil from roots of Chamaeciparis formosensis. Also reported found in apple, papaya, blackberry, cinnamomum, ginger, thymus, cheeses, cognac, Ocimum basilicum, rosemary, temoe lawak (Curcuma xanthorriza Roxb.) turmeric, sage, clary sage, ashanti pepper, German chamomile oil, eucalyptus oil and mastic gum leaf oil

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Isoborneol is a monoterpene and a component of several plant essential oils, showed dual viricidal activity against herpes simplex virus 1 (HSV-1).

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By the hydrolysis of isobornyl acetate, or by catalytic reduction of camphor (both d- and l-isomers); the optically inactive compound can by prepared by treating camphene with a 1:1 mixture of sulfuric acid and glacial acetic acid and then hydrolyzing the isobornyl acetate

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A geometrical isomer of borneol.

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Isoborneol is a monoterpene and a known antioxidant, which is a component of several plant essential oils.

Purification Methods

Crystallise isoborneol from EtOH or pet ether (b 60-80o). It sublimes in a vacuum. The 4-nitrobenzoyl derivative has m 153o. [Yager & Morgan J Am Chem Soc 57 2081 1935, Beilstein 6 II 80, 6 III 299, 6 IV 281.]

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