ChemicalBook >?? ???? >(+/-)-NFPS???
(+/-)-NFPS???
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(+/-)-NFPS??? ??
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- 2-8°C
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- DMSO: ~16mg/mL, ???
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??? ?? | Xn,N | ||
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?? ???? ?? | 22-50/53 | ||
????? | 22-24/25-61-60 | ||
????(UN No.) | UN 3077 9 / PGIII | ||
WGK ?? | 3 |
????(GHS): |
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?? ?: | Warning | |||||||||||||||||||||
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ALX 5407 Hydrochloride can be used in the preparation of amino acid derivatives as pharmaceuticals for treatment of neurological and neuropsychiatric disorders.Biochem/physiol Actions
ALX-5407 hydrochloride (NFPS hydrochloride) is a selective irreversible inhibitor of the glycine transporter GlyT1 with IC50 values of 3 nM for GlyT1 compared to 100 μM for GlyT2. ALX-5407 hydrochloride showed no activity at the inhibitory glycine receptor or glycine site of the NMDA receptor (IC50 > 100 mM).(+/-)-NFPS??? ?? ?? ? ???
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