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6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole

6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole ??? ???
?? ??:
1254036-71-9
???:
6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole
???(??):
CS-2340;Nemiralisib;GSK2269557 (free base);Nemiralisib(GSK2269557);gsk2269557(Nemiralisib);GSK 2269557;GSK-2269557;PI3Kδ inhibitor GS2269557;Nemiralisib, 10 mM in DMSO;Nemiralisib (GSK2269557 free base);2-(6-(1H-Indol-4-yl)-1H-indazol-4-yl)-5-((4-isopropylpiperazin-1-yl)methyl)oxazole
CBNumber:
CB63106826
???:
C26H28N6O
??? ??:
440.54
MOL ??:
1254036-71-9.mol

6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole ??

?? ?
706.2±70.0 °C(Predicted)
??
1.281±0.06 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO: 33.33 mg/mL (75.66 mM)
??? ??
Solid
?? ?? (pKa)
12.90±0.40(Predicted)
??
White to yellow
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole C??? ??, ??, ??

6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole ?? ?? ? ???

???

?? ??

6-(1H-indol-4-yl)-4-(5-((4-isopropylpiperazin-1-yl)methyl)oxazol-2-yl)-1H-indazole ?? ??

???( 43)?? ??
??? ?? ??? ?? ?? ? ??
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