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76610-84-9
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Cefbuperazone
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Tomiporan;Keiperazon;CEFBUPERAZONE;Cefbuperazone USP/EP/BP;The side chain of Cefbuperazone;(6R,7S)-7-((2R,3S)-2-(4-Ethyl-2,3-dioxo-1-p;methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-,(6r-(6-alpha,7-alpha,7(2r*,3s*));5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((2-(((4-ethyl-2,3-dio;xo-1-piperazinyl)carbonyl)amino)-3-hydroxy-1-oxobutyl)amino)-7-methoxy-3-(((1-;2,4-bis[(diaminomethylidene)amino]-3,5,6-trihydroxycyclohexyl dihydrogen phosphate
CBNumber:
CB6268448
???:
C22H29N9O9S2
??? ??:
627.65
MOL ??:
76610-84-9.mol

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118-120° (dec)
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Hygroscopic, -20°C Freezer, Under inert atmosphere
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Cefbuperazone is a second-generation cephalosporin antibiotic.

Antimicrobial activity

Cefbuperazone is a semisynthetic cephamycin antibiotic with properties similar to those of cefoxitin, but somewhat more active against B. fragilis and enterobacteria. It is not hydrolyzed by common β-lactamases and as a result its activity is not affected by inoculum size. It is not active against cefoxitin-resistant strains. It is available in Japan.

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