Dimethyl 5-hydroxyisophthalate
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Dimethyl 5-hydroxyisophthalate ??
- ???
- 162-164 °C (lit.)
- ?? ?
- 360.6±22.0 °C(Predicted)
- ??
- 1.284±0.06 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Room Temperature
- ???
- DMSO(?? ???), ???(?? ???)
- ??? ??
- ?? ?/?? ???
- ?? ?? (pKa)
- 8.33±0.10(Predicted)
- ??
- ??~?? ???
- ???
- ?? ?????.
- BRN
- 2650120
- InChIKey
- DOSDTCPDBPRFHQ-UHFFFAOYSA-N
- LogP
- 2.570 (est)
- CAS ??????
- 13036-02-7(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-36-37/39 | ||
| WGK ?? | 3 | ||
| TSCA | Yes | ||
| HS ?? | 29182900 |
Dimethyl 5-hydroxyisophthalate C??? ??, ??, ??
??? ??
off-white crystal powder??
Dimethyl 5-Hydroxyisophthalate is a useful synthetic intermediate in the synthesis of N,N?-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)carbamoyl)methoxy]-2,4,6-triiodoisophthalamide (B426310); a compound related to Ioversol( I737000) which is a nonionic, low osmolality, radiographic contrast agent.?? ??
Dimethyl 5-hydroxyisophthalate undergoes a base-catalyzed nucleophilic oxirane ring-opening addition reaction with allyl glycidyl ether, to afford 5-substituted derivatives of isophthalic acid. Influence of third component, i.e. a series of 1,ω-alkanediols on the copolymerization reaction of dimethyl 5-hydroxyisophthalate with poly(ethylene glycol) has been studied. Lipase-catalyzed condensation polymerization of dimethyl 5-hydroxyisophthalate with polyethylene glycol is reported.Dimethyl 5-hydroxyisophthalate ?? ?? ? ???
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Dimethyl 5-hydroxyisophthalate ?? ??
???( 205)?? ??
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