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Sennoside A

Sennoside A ??? ???
?? ??:
81-27-6
???:
Sennoside A
???(??):
Pursenni;SENNOSIDA;Glysennid;SENNOSIDE;PURSENNID;Nsc 112929;GLYSENNIDE;PURSENNIDE;SENNOSIDE A;Sennoside A1
CBNumber:
CB5663235
???:
C42H38O20
??? ??:
862.74
MOL ??:
81-27-6.mol
MSDS ??:
SDS

Sennoside A ??

???
>191oC (dec.)
??
D20 -164° (c = 0.1 in 60% acetone); D20 -147° (c = 0.1 in 70% acetone); D20 -24° (c = 0.2 in 70% dioxane)
?? ?
1144.8±65.0 °C(Predicted)
??
1.743±0.06 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
???
???? ??(??, ??), DMSO(??, ??)
??? ??
Solid
?? ?? (pKa)
3.31±0.40(Predicted)
??
????? ?? ?????
BRN
5723746
???
???
InChIKey
IPQVTOJGNYVQEO-KGFNBKMBSA-N
LogP
1.880 (est)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
?? ???? ?? 22
????? 22-45
WGK ?? 3
F ?????? 3-10
HS ?? 29173990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
2 0

Sennoside A C??? ??, ??, ??

??? ??

Light yellow powder

??

Sennoside A is used as a laxative in the treatment of constipation. In addition. it is hypothesized to induce cell proliferation and may be a potential carcinogenic agent.

Purification Methods

Sennoside A (bianthraquinonyl-bis-glucoside R,R-enantiomer) [81-27-6] M 862.7, m 220 -2 4 0o(dec), [ ] D -164o (c 0.1, Me2CO/H2O 6:4), [ ] D -24o (c 0.2, 70% aqueous dioxane). Sennoside A forms yellow crystals from aqueous acetone, 2-ethoxyethanol or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3403.]

Sennoside A ?? ?? ? ???

???

?? ??


Sennoside A ?? ??

???( 311)?? ??
??? ?? ??? ?? ?? ? ??
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Sennoside A ?? ??:

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