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(4-Chlorophenyl)(3-hydroxyphenyl)methanone
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(4-Chlorophenyl)(3-hydroxyphenyl)methanone ??
- ???
- 154–155°C
- ?? ?
- 410.3±30.0 °C(Predicted)
- ??
- 1.307±0.06 g/cm3(Predicted)
- ?? ?? (pKa)
- 8.97±0.10(Predicted)
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(4-Chlorophenyl)(3-hydroxyphenyl)methanone C??? ??, ??, ??
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4’-Chloro-3-hydroxy-benzophenone is an impurity of Fenofibric acid (F248650), which is an active metabolite of Fenofibrate (F248640). 4’-Chloro-3-hydroxy-benzophenone can also be used to develop treatments for tuberculosis.?? ??
Preparation by diazotization of 3-amino-4?- chlorobenzo-phenone (SM), followed by hydrolysis of the diazonium salt obtained (81%), (84%). SM was obtained by Friedel–Crafts acylation of chlorobenzene with m-nitro-benzoyl chloride, followed by reduction of the resulting 4-chloro- 3?-nitrobenzophenone.(4-Chlorophenyl)(3-hydroxyphenyl)methanone ?? ?? ? ???
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(4-Chlorophenyl)(3-hydroxyphenyl)methanone ?? ??
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