ChemicalBook >?? ???? >?? ???>??? ?? ?? ???>???>3-HYDROXYPYRAZINE-2-CARBOXAMIDE

3-HYDROXYPYRAZINE-2-CARBOXAMIDE

3-HYDROXYPYRAZINE-2-CARBOXAMIDE ??? ???

?? ??:: 55321-99-8

???:: 3-HYDROXYPYRAZINE-2-CARBOXAMIDE

???(??):: Favipiravir Impurity;(3-BROMOPYRIDIN-4-...;T-1105, 10 mM in DMSO;Favipiravir intermediate;Favipiravir Desfluoro Impurity;3-HYDROXYPYRAZINE-2-CARBOXAMINE;3-HYDROXYPYRAZINE-2-CARBOXAMIDE;3-Hydroxy-2-pyrazinecarboxamide;Pyrazine-2-carboxamide, 3-hydroxy-;3-Hydroxypyrazine-2-carboxamide>

CBNumber:: CB5478811

???:: C5H5N3O2

??? ??:: 139.11

MOL ??:: 55321-99-8.mol

?? ?? 189

3-HYDROXYPYRAZINE-2-CARBOXAMIDE ??

???: ca 270℃

??: 1.63±0.1 g/cm3(Predicted)

?? ??: Sealed in dry,Room Temperature

???: DMSO(?? ???), ?? ??(?? ???)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 10.69±0.40(Predicted)

??: ?? ???? ????

?? ??(λmax): 348nm(lit.)

???: ???

?? ? ?? ??
?? ? ???? ?? (GHS)

?? ???? ??	36/37/38
?????	26-37
HS ??	29339900

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P304+P340	???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405	???? ?????.

NFPA 704

	1
2		0

3-HYDROXYPYRAZINE-2-CARBOXAMIDE C??? ??, ??, ??

??? ??

White crystalline powder

??

Apart from biological importance of pyridine-2-carboxamide (picolinamide, pia) as well as of its derivatives such as 3-hydroxypyridine-2-carboxamide (3-OHpia), as ligands they have found their extensive application in coordina- tion chemistry in crystal engineering .

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 78, 1949 DOI: 10.1021/ja01169a023

3-HYDROXYPYRAZINE-2-CARBOXAMIDE ?? ?? ? ???

???

?? ??

2-????????,6-????-3,4-?????-3-??- 3-Chloropyrazine-2-carbonitrile

3-HYDROXYPYRAZINE-2-CARBOXAMIDE ?? ??

???( 189)?? ??

???	??	???	??	?? ?	??
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3-HYDROXYPYRAZINE-2-CARBOXAMIDE ?? ??:

Methyl 6-bromo-3-oxo-3,4-dihydropyrazine-2-carboxylate 6-Bromo-3-chloropyrazine-2-carbonitrile 3-Chloropyrazine-2-carbonitrile Pyrazinecarboxamide, 3,6-difluoro- (9CI) 3-OXO-3,4-DIHYDROPYRAZINE-2-CARBONITRILE 2-Pyrazinecarbonitrile, 6-fluoro-3,4-dihydro-3-oxo-, coMpd. with N-cyclohexylcyclohexanaMine (1:1) 2-HYDROXYPYRAZINE 2-Pyrazinecarbonitrile, 3-fluoro- Cefepime 3,6-DibroMopyrazine-2-carbonitrile Pyrazinecarboxamide, 6-fluoro- (9CI) Pyrazinecarboxamide, 5-fluoro-3,4-dihydro-3-oxo- (9CI) 3-HYDROXYPYRAZINE-2-CARBOXAMIDE (3-METHOXY-PYRAZIN-2-YL)-MORPHOLIN-4-YL-METHANONE 5-Hydroxypyrazine-2-carboxamide BUTTPARK 91\04-18 SALOR-INT L101621-1EA 3-HYDROXY-5,6-DIPHENYL-2-PYRAZINECARBOXAMIDE

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