The acute oral LD50 value in rats was reported as 3.37 ± 0.405 g/kg and the acute dermal LD50 value in rabbits as approximately 5 g/kg (McGee, 1974). The oral LD50 of manila elemi in mice was > 5 g/kg (Toida, 1971).
The tree grows wild or cultivated in the Philippines. Elemi, a resin, is the pathological exudate flowing from incisions
made on the trunk bark. The largest resin production coincides with the appearance of the leaves at the beginning of the rainy season.
The gum-resin outflows as a soft, yellowish-white mass that hardens to a wax-like consistency on exposure to air. The part used is the
resinous exudate. Elemi has a characteristic green, fresh, lemon-like, agreeable, balsamic odor.
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As a pathological exudation of the tree C. commune L. or C. luzonicum Mig (Fam. Burseraceae) (Guenther, 1950).
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By steam distillation from the crude resin of C. commune L. or C. luzonicum Mig (Fenarolis Handbook of Flavor Ingredients, 1975).
