Anti-EL;Anti-EDL;Anti-LIPG;Anti-PRO719;Anti-Endothelial lipase;Anti-Lipase, endothelial;Anti-Endothelial cell-derived lipase;Anti-LIPG antibody produced in rabbit;Anti-TBCEL (81-95) antibody produced in rabbit;Monoclonal Anti-LIPG antibody produced in mouse
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
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LIPG (lipase, endothelial) is an important member of the triglyceride lipase gene family and lipase subfamily. It consists of N-terminal and C-terminal structural domain connected by a hinge region. In its N-terminal domain, it contains a catalytic triad of serine, aspartic acid, and histidine. The catalytic triad is covered by a lid, which possesses substrate specificity for triglyceride or phospholipid substrates. Endothelial derived lipase is expressed in placenta, liver, lung, ovary, kidney, thyroid gland, and testis.
Biochem/physiol Actions
LIPG (lipase, endothelial) is involved in the lipoprotein catabolism in the plasma compartment. The C-terminal domain of LIPG binds to the triglycerides, lipoprotein lipase, hepatic lipase, and phospholipids in plasma lipoproteins. It directly binds to the lipoproteins of the heparan sulfate proteoglycans and hydrolyzes triglycerides and phosphatidylcholine at the specific positions.
