ChemicalBook >?? ???? >N-(4,5-?????-1H-????-2-?)-6-??????

N-(4,5-?????-1H-????-2-?)-6-??????

N-(4,5-?????-1H-????-2-?)-6-?????? ??? ???

?? ??:: 91147-43-2

???:: N-(4,5-?????-1H-????-2-?)-6-??????

???(??):: N-(4,5-?????-1H-????-2-?)-6-??????

???:: N-(4,5-Dihydro-1H-iMidazol-2-yl)-6-quinoxalinaMine

???(??):: Brimonidine Impurity 3;Brimonidine EP Impurity A;N-(Imidazolidin-2-ylidene)quinoxalin-6-amine;Debromo Brimonidine;Brimonidine EP Imp A;Desbromo Brimonidine;Brimonidine Impurity A;Brimonidine impurity II;Brimonidine Tartrate EP Impurity A;N-(Imidazolidin-2-ylidene)quinoxali

CBNumber:: CB52696013

???:: C11H11N5

??? ??:: 213.24

MOL ??:: 91147-43-2.mol

?? ?? 86

N-(4,5-?????-1H-????-2-?)-6-?????? ??

???: >210°C (dec.)

?? ?: 393.9±45.0 °C(Predicted)

??: 1.44±0.1 g/cm3(Predicted)

?? ??: Hygroscopic, -20°C Freezer, Under inert atmosphere

???: DMSO(?? ???, ??), ???(?? ???, ??? ??)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 8.36±0.10(Predicted)

??: ???

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??		P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??		P264, P280, P305+P351+P338,P337+P313P

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P501	...? ??? / ??? ?? ???.

N-(4,5-?????-1H-????-2-?)-6-?????? C??? ??, ??, ??

??

N-(4,5-Dihydro-1H-imidazol-2-yl)-6-quinoxalinamine is an analogue of Brimonidine (B677520), a α2-Adrenoceptor agonist and antiglaucoma agent.

N-(4,5-?????-1H-????-2-?)-6-?????? ?? ?? ? ???

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N-(4,5-?????-1H-????-2-?)-6-?????? ?? ??

???( 86)?? ??

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N-(4,5-?????-1H-????-2-?)-6-?????? ?? ??:

Brimonidine Impurity 14 5-BROMO-6-ISOTHIOCYANATE QUINOXALINE Thiourea, N-(2-aminoethyl)-N'-(5-bromo-6-quinoxalinyl)- 5-Bromoquinoxalin-6-amine 5-Bromoquinazolin-6-ylthiourea Brimonidine Impurity 6 6-Aminoquinoxaline Brimonidine Dimer 4,5-Didehydro BriMonidine 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine BriMonidine-2,3-dione Brimonidine Related Impurity 3 5-bromo-N-(4,4,5,5-tetradeuterio-1H-imidazol-2-yl)quinoxalin-6-amine Hydroxy Brimonidine Brimonidine Tartrate Impurity 4 Brimonidine Impurity E Brimonidine Tartrate Brimonidine

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