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??-??-3-????-2,4,6-???????????

??-??-3-????-2,4,6-???????????
??-??-3-????-2,4,6-??????????? ??? ???
?? ??:
96-84-4
???:
??-??-3-????-2,4,6-???????????
???(??):
??-??-3-????-2,4,6-???????????
???:
ALPHA-ETHYL-3-HYDROXY-2,4,6-TRIIODOHYDROCINNAMIC ACID
???(??):
teridax;Jodoprol;Iophenoic;Tiloshade;Trilombrine;IophenoicAcid;IOPHENOXIC ACID;triiodoethionicacid;alpha-ethyl-beta-(3-hydrox;Acide iophenoique [INN-French]
CBNumber:
CB5266250
???:
C11H11I3O3
??? ??:
571.92
MOL ??:
96-84-4.mol

??-??-3-????-2,4,6-??????????? ??

???
146-148 °C (lit.)
?? ?
459.0±45.0 °C(Predicted)
??
2.2890 (estimate)
?? ?? (pKa)
pKa 7.5(H2O,(extrap)) (Uncertain)
??? ??
solid
Merck
13,5077
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22-36/37/38
????? 26-37/39
WGK ?? 3
RTECS ?? MW5280000
?? LD50 i.v. in mice: 374 mg/kg (Hoppe)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

??-??-3-????-2,4,6-??????????? C??? ??, ??, ??

??

α-Ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid (iophenoxic acid ) was used as marker in “bait acceptance” studies conducted on various animal species. It was used in the direct quantitation of iophenoxic acid in porcine serum samples by a liquid chromatographic-electrospray ionization mass spectrometric technique.

?? ??

α-Ethyl-3-hydroxy-2,4,6-triiodohydrocinnamic acid (Iophenoxic acid ) is an organic, iodine-containing compound. Iophenoxic acid is an iodinated radiocontrast agent, its clinical use has been withdrawn due to its exceptionally long half-life in the body, since it has high-affinity binding to human serum albumin (HSA). Structural basis of its interaction with HSA has been evaluated.

??-??-3-????-2,4,6-??????????? ?? ?? ? ???

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??-??-3-????-2,4,6-??????????? ?? ??

???( 27)?? ??
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