N-[3-????-1,1-??(??????)-3-(4-????)???]??????

N-[3-????-1,1-??(??????)-3-(4-????)???]?????? ??? ???

?? ??:: 162361-41-3

???:: N-[3-????-1,1-??(??????)-3-(4-????)???]??????

???(??):: N-[3-????-1,1-??(??????)-3-(4-????)???]??????

???:: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide

???(??):: N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]acetamide;Acetamide, N-[3-hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]-

CBNumber:: CB52657977

???:: C21H35NO4

??? ??:: 365.51

MOL ??:: 162361-41-3.mol

?? ?? 2

N-[3-????-1,1-??(??????)-3-(4-????)???]?????? ??

?? ?: 603.0±55.0 °C(Predicted)

??: 1.088±0.06 g/cm3 (20 ºC 760 Torr)

???: ???，??????， DMSO?????

?? ?? (pKa): 14.11±0.10(Predicted)

??? ??: ??

??? ??: ??? ??

??: ???

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N-[3-????-1,1-??(??????)-3-(4-????)???]?????? C??? ??, ??, ??

??

N-[3-Hydroxy-1,1-bis(hydroxymethyl)-3-(4-octylphenyl)propyl]-acetamide is an intermediate used in the synthesis of 1-Hydroxy Fingolimod Hydrochloride (H942605), which is an impurity of the drug Fingolimond (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.

N-[3-????-1,1-??(??????)-3-(4-????)???]?????? ?? ?? ? ???

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N-[3-????-1,1-??(??????)-3-(4-????)???]?????? ?? ??

???( 2)?? ??

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Shanghai Hao Zhun Biological Technology Co., Ltd.	--	info@zzsrm.com	CHINA	6650	58
Hangzhou Utanpharma Biology Co., Ltd.	--	sales@utanpharma.com	China	217	50

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