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2,4,7-????????[2,3-d]????

2,4,7-????????[2,3-d]????
2,4,7-????????[2,3-d]???? ??? ???
?? ??:
938443-20-0
???:
2,4,7-????????[2,3-d]????
???(??):
2,4,7-????????[2,3-d]????
???:
2,4,7-Trichloropyrido[2,3-d]pyrimidine
???(??):
100232;2,4,7-Trichloropyrido[2,3...;2,4,7-Trichloropyrido[2,3-d]pyrimidine;Pyrido[2,3-d]pyriMidine, 2,4,7-trichloro-;2,4,7-Trichloropyrido[2,3-d]pyrimidine ISO 9001：2015 REACH
CBNumber:
CB52474792
???:
C7H2Cl3N3
??? ??:
234.47
MOL ??:
938443-20-0.mol

2,4,7-????????[2,3-d]???? ??

?? ?
316.4±42.0 °C(Predicted)
??
1.685±0.06 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
?? ?? (pKa)
-2.53±0.30(Predicted)
InChIKey
DNFDLCRLLQVUQK-UHFFFAOYSA-N
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T
?? ???? ?? 25-41
????? 26-39-45
????(UN No.) UN 2811 6.1 / PGIII
WGK ?? 3
HS ?? 2933998090
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H301 ??? ??? ?? ?? ?? - ?? ?? 3 ?? GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P280, P305+P351+P338, P310
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P310 ???? ?? ????(??)? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.

2,4,7-????????[2,3-d]???? C??? ??, ??, ??

??

2,4,7-Trichloropyrido[2,3-d]pyrimidine is used in the synthetic preparation of dual mTORC1/mTORC2 inhibitors and the discovery of AZD8055 and AZD2014 as potential antitumor agents.

2,4,7-????????[2,3-d]???? ?? ?? ? ???

???

Pyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione 2,6-Dichloronicotinic acid 7-??????[2,3-d]????-2,4-?? 2-???-6-????????? 2-???-5-??????-3-?????

?? ??

4-(2,7-???????[2,3-d]????-4-?)????

2,4,7-????????[2,3-d]???? ?? ??

???( 113)?? ??
??? ?? ??? ?? ?? ? ??
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2,4,7-????????[2,3-d]???? ?? ??:

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