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4-[5-(4-?????????)-2-??]??????????

4-[5-(4-?????????)-2-??]??????????
4-[5-(4-?????????)-2-??]?????????? ??? ???
?? ??:
55368-40-6
???:
4-[5-(4-?????????)-2-??]??????????
???(??):
4-[5-(4-?????????)-2-??]??????????
???:
Furamidine dihydrochloride
???(??):
DB75;DB-75;WR-199385;Furamidine;Furamidine HCl;DB75 dihydrochloride;FuraMidine Dihydrochloride;Furamidine (hydrochloride);NSC 305831 dihydrochloride;DB 75, DB75, NSC 305831, WR199385
CBNumber:
CB51518554
???:
C18H16N4O
??? ??:
0
MOL ??:
55368-40-6.mol
MSDS ??:
SDS

4-[5-(4-?????????)-2-??]?????????? ??

???
400-401 °C(Solv: ethanol (64-17-5))
?? ??
-20°C
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??
???? ????
???
H2O: 1mg/mL, clear (warmed)
???
???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312 ???? ??? ????(??)? ??? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
0
2 0

4-[5-(4-?????????)-2-??]?????????? C??? ??, ??, ??

??? ??

Yellow Solid

??

Furamidine is a diphenylfuran compound belonging to an important class of antimicrobial and antiparasitic agents. Furamidine and its analogues also display antitumor activities and showed antiproliferative activities against various tumor cell lines.

?? ??

Furamidine dihydrochloride is an analog of the aromatic drug pentamidine and a substrate of the organic cation transporter 1 (OCT1). A number of prodrugs of furamidine dihydrochloride are being synthesised and are in clinical trial stages.

4-[5-(4-?????????)-2-??]?????????? ?? ?? ? ???

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4-[5-(4-?????????)-2-??]?????????? ?? ??

???( 43)?? ??
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