ChemicalBook >?? ???? >(+/-)-N-3-??????
(+/-)-N-3-??????
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(+/-)-N-3-?????? ??
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- 134-136°C
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- 1.190±0.06 g/cm3(Predicted)
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- -20°C Freezer
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- DMSO(?? ???), ???(?? ???)
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- 8.02±0.70(Predicted)
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(+/-)-N-3-?????? C??? ??, ??, ??
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(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol. (+)-N-3-benzylnirvanol and (–)-N-3-benzylnirvanol are inhibitors of the cytochrome P450 (CYP) isoform CYP2C19 (Kis = 0.25 and 5.3 μM, respectively). (±)-N-3-Benzylnirvanol (20 mg/kg, i.p.) lowers plasma levels of cholesterol in mice.??? ??
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It is a potent and selective human CYP2C19 inhibitor(+/-)-N-3-?????? ?? ?? ? ???
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(+/-)-N-3-?????? ?? ??
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