ChemicalBook >?? ???? >RJR-2429 2HCL
RJR-2429 2HCL
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RJR-2429 2HCL ??
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- 295.6±15.0 °C(Predicted)
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- 1.11±0.1 g/cm3(Predicted)
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- Desiccate at RT
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- H2O: 5 mg/mL
- ?? ?? (pKa)
- 9.41±0.40(Predicted)
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| WGK ?? | 3 |
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RJR-2429 2HCL C??? ??, ??, ??
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RJR 2429 is a potent AChR agonist.???? ??
Potent nAChR agonist that displays selectivity for α 4 β 2 (K i = 1 nM) and α 1 β γ δ subtypes (EC 50 values are 297 and 55 nM respectively). Induces dopamine release from striatal neurons (EC 50 = 2 nM) and inhibits ion flux in thalamic neurons (IC 50 = 154 nM). Also putative α 3 β 4 agonist that potentiates catecholamine release.RJR-2429 2HCL ?? ?? ? ???
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RJR-2429 2HCL ?? ??
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