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??(2E)-???[(4-?????)??????]????

??(2E)-???[(4-?????)??????]????
??(2E)-???[(4-?????)??????]???? ??? ???
?? ??:
27143-09-5
???:
??(2E)-???[(4-?????)??????]????
???(??):
??(2E)-???[(4-?????)??????]????
???:
ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE
???(??):
Apixaban-10;Apixaban Impurity R;Apixaban Impurity S1;Impurity of apixaban374;Apixaban Related Compound 7;Apixaban related impurities 6;Ethyl 2-chloro-2-[2-(4-chlorophenyl)hydrazono]-;ETHYL (2E)-CHLORO[(4-CHLOROPHENYL)HYDRAZONO]ACETATE;ethyl (2E)-chloro[(4-chlorophenyl)hydrazono]ethanoate;Ethyl (4-chlorophenylhydrazono)chloromethylcarboxylate
CBNumber:
CB4408853
???:
C10H10Cl2N2O2
??? ??:
261.1
MOL ??:
27143-09-5.mol

??(2E)-???[(4-?????)??????]???? ??

???
150 °C
?? ?
337.1±44.0 °C(Predicted)
??
1.33±0.1 g/cm3(Predicted)
?? ??
-20°C Freezer, Under inert atmosphere
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
11.04±0.10(Predicted)
??
?? ????? ?? ?????
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2915390090
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P280, P305+P351+P338, P310
H330 ???? ???? ?? ?? ?? ?? ?? 1, 2 ?? GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
??????:
P260 ??·?·??·???·??·...·????? ???? ???.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P284 ?? ???? ?????.
P302+P352 ??? ??? ??? ?? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.

??(2E)-???[(4-?????)??????]???? C??? ??, ??, ??

??

(Z)?-?Ethyl 2-?chloro-?2-?(2-?(4-?chlorophenyl)?hydrazono)?acetate is a reagent used in the preparation of pyrimidine and pyrimidinone-based compounds for their use as antimicrobials.

??(2E)-???[(4-?????)??????]???? ?? ?? ? ???

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??(2E)-???[(4-?????)??????]???? ?? ??

???( 81)?? ??
??? ?? ??? ?? ?? ? ??
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??(2E)-???[(4-?????)??????]???? ?? ??:

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