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TC HSD 21

TC HSD 21 ??? ???
?? ??:
330203-01-5
???:
TC HSD 21
???(??):
TC HSD 21;5-(3-Bromo-4-hydroxybenzylidene)-3-(4-methoxyphenyl)-2-thioxothiazolidin-4-one;5-[(3-Bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone;4-Thiazolidinone, 5-[(3-bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-;5-[(3-bromo-4-hydroxyphenyl)methylidene]-3-(4-methoxyphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one
CBNumber:
CB43037546
???:
C17H12BrNO3S2
??? ??:
422.32
MOL ??:
330203-01-5.mol

TC HSD 21 ??

?? ?
549.6±60.0 °C(Predicted)
??
1.72±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
Soluble to 100 mM in DMSO
??? ??
??
?? ?? (pKa)
7.51±0.35(Predicted)
??
Light yellow to yellow
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

TC HSD 21 C??? ??, ??, ??

??

TC HSD 21 is a novel and potent inhibitor of 17β-hydroxysteroid dehydrogenase type 3.

TC HSD 21 ?? ?? ? ???

???

?? ??

TC HSD 21 ?? ??

???( 36)?? ??
??? ?? ??? ?? ?? ? ??
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