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N-Hydroxyethylphthalimide

N-Hydroxyethylphthalimide ??? ???
?? ??:
3891-07-4
???:
N-Hydroxyethylphthalimide
???(??):
N-(2-HYDROXYETHYL)PHTHALIMIDE;AKOS BBS-00004429;TIMTEC-BB SBB003638;2-PHTHALIMIDOETHANOL;N-Hydroxyethylphthal;Alogliptin impurity Q;Amlodipine Impurity Q;N-hydroethyl phthalimide;N-HYDROXYETHYLPHTHALIMIDE;2-Hydroxyethylphthalimide
CBNumber:
CB4241489
???:
C10H9NO3
??? ??:
191.18
MOL ??:
3891-07-4.mol
MSDS ??:
SDS

N-Hydroxyethylphthalimide ??

???
126-128 °C(lit.)
?? ?
326.92°C (rough estimate)
??
1.2722 (rough estimate)
???
1.5310 (estimate)
?? ??
Inert atmosphere,Room Temperature
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
14.40±0.10(Predicted)
??? ??
??? ??
??
???
BRN
147214
InChIKey
MWFLUYFYHANMCM-UHFFFAOYSA-N
CAS ??????
3891-07-4(CAS DataBase Reference)
NIST
N-2-hydroxyethyl phthalimide(3891-07-4)
EPA
1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxyethyl)- (3891-07-4)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 22-26-36/37/39-24/25
WGK ?? 3
TSCA Yes
HS ?? 29251900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
1
0 0

N-Hydroxyethylphthalimide C??? ??, ??, ??

??? ??

white crystalline powder

??

N-(2-Hydroxyethyl)phthalimide is used as a reagent to synthesize (-)-R-rolipram is a phosphodiesterase 4 inhibitor that is used to treat depression. N-(2-Hydroxyethyl)phthalimide is also used as a reagent to synthesize FR252921, a compound that acts as an immunosuppressant. Amlodipine Impurity 6

?? ??

N-(2-Hydroxyethyl)phthalimide is the precursor for chloromethyl ethers used in the synthesis of purine acyclic nucleosides.

N-Hydroxyethylphthalimide ?? ?? ? ???

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N-Hydroxyethylphthalimide ?? ??

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N-Hydroxyethylphthalimide ?? ??:

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