????-4-?[1,1'-???]-2-??????
????-4-?[1,1'-???]-2-?????? ??? ???
?? ??:
171722-92-2
???:
????-4-?[1,1'-???]-2-??????
???(??):
????-4-?[1,1'-???]-2-??????
???:
piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate
???(??):
16403-A2 ,9291;4-PIPERIDYL N-(2-BIPHENYL)CARBAMATE;piperidin-4-yl biphenyl-2-ylcarbamate;piperidin-4-yl N-(2-phenyphenyl)carbamate;piperidin-4-yl N-(2-phenylphenyl)carbamate;piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate;piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate;Biphenyl-2-ylcarbamic Acid Piperidin-4-yl Ester;N-[1,1'-biphenyl]-2-yl,4-piperidinyl ester (BPC-H);1,1'-Biphenyl]-2-yl carbamic acid 4-piperidinyl ester
CBNumber:
CB33053613
???:
C18H20N2O2
??? ??:
296.36
MOL ??:
171722-92-2.mol
????-4-?[1,1'-???]-2-?????? ??
?? ?
427.1±45.0 °C(Predicted)
??
1.19±0.1 g/cm3(Predicted)
?? ?? (pKa)
13.34±0.70(Predicted)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
????(GHS):
?? ?:
Warning
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H302 ??? ???
?? ?? ?? - ??
?? 4
??
P264, P270, P301+P312, P330, P501
H315 ??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
????-4-?[1,1'-???]-2-?????? C??? ??, ??, ??
??
4-Piperidyl N-(2-biphenylyl)carbamate is an intermediate in the synthesis of Des-4''(methylpiperidine-4-carboxamide)-4''-hydroxymethyl Revefenacin (D119860), an impurity of Revefenacin (R279600). Revefenacin is a pharmaceutical drug for the treatment of chronic obstructive pulmonary diseases.
????-4-?[1,1'-???]-2-?????? ?? ?? ? ???
???
?? ??
????-4-?[1,1'-???]-2-?????? ?? ??
???( 118)?? ??
China 111
India 7
Global 118
????-4-?[1,1'-???]-2-?????? ?? ??:
![????-4-?[1,1'-???]-2-??????](CAS/20180702/GIF/171722-92-2.gif)
