diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate ??? ???
?? ??:
120533-76-8
???:
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate
???(??):
BML-278;BML278|||BML 278;BML-278, SIRT activator;DI ETHYL 1 BENZYL 4 PHENYL 4H PYRIDINE 3-5 DICARBOXYLATE;Diethyl 1-benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate;diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-phenyl-1-(phenylmethyl)-, 3,5-diethyl ester
CBNumber:
CB33050728
???:
C24H25NO4
??? ??:
391.46
MOL ??:
120533-76-8.mol
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate ??
???
139-141 °C(Solv: cyclohexane (110-82-7); benzene (71-43-2))
?? ?
525.5±50.0 °C(Predicted)
??
1.183±0.06 g/cm3(Predicted)
?? ??
Sealed in dry,Room Temperature
???
DMSO? ?????(?? 5mg/ml).
??? ??
??
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?? ?? (pKa)
2.05±0.70(Predicted)
??
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??? ?? ?????? 2? ?? ??????. DMSO ??? -20°C?? ?? 3?? ?? ??? ? ????.
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?? ? ?? ??
?? ? ???? ?? (GHS)
????(GHS):
?? ?:
Warning
??·?? ??:
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?? ??
P- ??
H302
??? ???
?? ?? ?? - ??
?? 4
??
P264, P270, P301+P312, P330, P501
H315
??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319
?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335
?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P261
??·?·??·???·??·...·????? ??? ????.
P305+P351+P338
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate C??? ??, ??, ??
??
Diethyl 1-Benzyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate is a cell-permeable and potent SIRT activator that induces cell cycle arrest. SIRT modulators have therapeutic potential the treatment of cancer, cardiovascular, metabolic, inflammatory, and neurodegenerative diseases.
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate ?? ?? ? ???
???
?? ??
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate ?? ??
???( 47)?? ??
China 41
India 1
United States 5
Global 47
diethyl 1-benzyl-1,4-dihydro-4-phenylpyridine-3,5-dicarboxylate ?? ??: