???????
|
|
??????? ??
- ???
- 170°
- ??
- D20 -58.7° (c = 0.5 in ethanol)
- ?? ?
- 485.9±45.0 °C(Predicted)
- ??
- 1.17±0.1 g/cm3(Predicted)
- ?? ??
- 2-8°C
- ???
- DMSO: ≥10mg/mL
- ?? ?? (pKa)
- 14.79±0.40(Predicted)
- ??? ??
- ??
- ??
- ?? ????? ?????
- optical activity
- [α]/D -48 to -68°
- InChI
- InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/s3
- InChIKey
- CCCIJQPRIXGQOE-XWSJACJDSA-N
- SMILES
- [C@@]12([H])CC[C@@](O)(C)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,7,21,r|
- CAS ??????
- 965-93-5(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | 3 | ||
|---|---|---|---|
| DEA Controlled Substances | CSCN: 4000 CSA SCH: Schedule III NARC: No |
| ????(GHS): |
|
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ?? ?: | Warning | ||||||||||||||
| ??·?? ??: |
|
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| ??????: |
|
??????? C??? ??, ??, ??
??
Methyltrienolone ?? ??? ?? ?? ????? ??? ????? ?????? ??? ?? ???? ??? ? ????. Methyltrienolone ?? ??? ?????? ??? ?? ??? ??? ?????. Methyltrienolone ?? ??? ?? ? ???? ??? ? ?? ? ????.??
Methyltrienolone, also called metribolone, is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug or a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and prostatic tumors.??? ??
Pale Yellow Solid??
Methyltrienolone is a synthetic derivative of testosterone that is used in the medical field as an androgen and anabolic agent. It has been used to treat breast cancer, prostate cancer, and other cancers that are sensitive to hormones.??
ChEBI: Methyltrienolone, also known as 7beta-hydroxy-17-methylestra-4,9,11-trien-3-one, is a synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. It has a role as an androgen. It is an anabolic androgenic steroid, a 17beta-hydroxy steroid and a 3-oxo steroid. It derives from a hydride of an estrane.?? ??
https://en.wikipedia.org/wiki/Metribolonehttps://www.drugbank.ca/drugs/DB02998
https://pubchem.ncbi.nlm.nih.gov/compound/Methyltrienolone
Kazlauskas R. (2010) Designer Steroids. In: Thieme D., Hemmersbach P. (eds) Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology, vol 195. Springer, Berlin, Heidelberg
??????? ?? ?? ? ???
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???( 158)?? ??
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CHLOROPHOSPHONAZO III
Trenbolone
Trenbolone acetate
(-)-2-[METHYLAMINO]-1-PHENYLPROPANE
Gestrinone
17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one
Altrenogest
Methyltrienolone
methyltrienolone binding protein
Methyltrienolone(Metribolone)
METRIBOLONE(METHYLTRIENOLONE)
METHYLTRIENOLONE, [17 ALPHA-METHYL-3H]-