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AC-YVAD-AFC

AC-YVAD-AFC ??? ???
?? ??:
219137-85-6
???:
AC-YVAD-AFC
???(??):
AC-YVAD-AFC;AC-TYR-VAL-ALA-ASP-AFC;M.W. 719.67 C33H36F3N5O10;CASPASE-1 SUBSTRATE XII, FLUOROGENIC;CASPASE 1 (ICE) SUBSTRATE 2F, FLUOROGENIC;AC-TYR-VAL-ALA-ASP-7-AMINO-4-TRIFLUOROMETHYL COUMARIN;N-ACETYL-TYR-VAL-ALA-ASP 7-AMIDO-4-TRIFLUOROMETHYLCOUMARIN;N-Acetyl-Tyr-Val-Ala-Asp-(7-amino-4-trifluoromethylcoumarin);Caspase-1 Substrate VI, Fluorogenic - CAS 219137-85-6 - Calbiochem;L-α-Asparagine, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-
CBNumber:
CB2753902
???:
C33H36F3N5O10
??? ??:
719.66
MOL ??:
219137-85-6.mol
MSDS ??:
SDS

AC-YVAD-AFC ??

???
>190°C (dec.)
?? ?
1084.6±65.0 °C(Predicted)
??
1.416±0.06 g/cm3(Predicted)
?? ??
−20°C
???
DMSO (?? ???), ??? (?? ???)
??? ??
??
?? ?? (pKa)
4.09±0.10(Predicted)
??
???

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WGK ?? 3

AC-YVAD-AFC C??? ??, ??, ??

??

Ac-YVAD-AFC is a substrate whose amino acids YVAD have been shown to be a preferred cleavage site for caspase-1 and -4. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

???? ??

Fluorogenic peptide substrate for caspase-1 (ICE).

AC-YVAD-AFC ?? ?? ? ???

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AC-YVAD-AFC ?? ??

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