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1-beta-D-Arabinofuranosylcytosine hydrochloride

1-beta-D-Arabinofuranosylcytosine hydrochloride ??? ???
?? ??:
69-74-9
???:
1-beta-D-Arabinofuranosylcytosine hydrochloride
???(??):
ARA-C;ac1075;ALEXAN;u-19920a;Cylocide;Ara-c.Ha;Cytarbine;ARA-C HCL;CYTARABINE HCL;ara-chydrochloride
CBNumber:
CB2260590
???:
C9H14ClN3O5
??? ??:
279.68
MOL ??:
69-74-9.mol
MSDS ??:
SDS

1-beta-D-Arabinofuranosylcytosine hydrochloride ??

???
197-198 °C(lit.)
?? ??
2-8°C
???
insoluble in EtOH; ≥14.2 mg/mL in DMSO; ≥64.2 mg/mL in H2O
??? ??
?? ??
??
???? ?????
???? ??
synthetic (inorganic)
???
????. ?? ??. ?? ???? ???? ????.
InChI
InChI=1/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/s3
InChIKey
KCURWTAZOZXKSJ-XKIMMOKZSA-N
SMILES
N1([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)C=CC(N)=NC1=O.[H]Cl |&1:1,3,6,8,r|
CAS ??????
69-74-9(CAS DataBase Reference)
EPA
Cytarabine hydrochloride (69-74-9)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 36-43-63
????? 26-36/37
WGK ?? 3
RTECS ?? HA5500000
?? ?? IRRITANT
HS ?? 29389090
?? LD50 oral in rat: > 3200mg/kg
???? ?? KE-01895
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H317 ????? ?? ??? ??? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H341 ???? ??? ??? ??? ??? (????? ???? ????? ???? ???? ???? ??? ?? ????? ??? ???? ??) ???? ???? ?? ?? 2 ?? P201,P202, P281, P308+P313, P405,P501
H361 ?? ?? ????? ??? ??? ??? ??? ???? ?? ?? 2 ?? P201, P202, P281, P308+P313, P405,P501
??????:
P201 ?? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P308+P313 ?? ?? ??? ???? ???? ??· ??? ????.
NFPA 704
0
2 0

1-beta-D-Arabinofuranosylcytosine hydrochloride MSDS


1-beta-D-Arabinofuranosylcytosine hydrochloride

1-beta-D-Arabinofuranosylcytosine hydrochloride C??? ??, ??, ??

??? ??

Crystalline

??

Antiviral.

?? ??

Crystals (from aqueous ethanol) or fluffy white powder.

??? ?? ??

Water soluble. Hydrolysis occurs readily, especially with acid.

?? ???

1-beta-D-Arabinofuranosylcytosine hydrochloride undergoes decomposition in acidic solutions.

????

Flash point data for 1-beta-D-Arabinofuranosylcytosine hydrochloride are not available; however, 1-beta-D-Arabinofuranosylcytosine hydrochloride is probably combustible.

Safety Profile

Poison by intravenous route.Moderately toxic by intraperitoneal and subcutaneousroutes. Experimental reproductive effects. A human eyeirritant. Mutation data reported. When heated todecomposition it emits very toxic fumes of NOx and HCl.

1-beta-D-Arabinofuranosylcytosine hydrochloride ?? ?? ? ???

???

?? ??


1-beta-D-Arabinofuranosylcytosine hydrochloride ?? ??

???( 314)?? ??
??? ?? ??? ?? ?? ? ??
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1-beta-D-Arabinofuranosylcytosine hydrochloride ?? ??:

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