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382-45-6
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Adrenosterone
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11-KETOANDROSTENEDIONE;Nsc12166;s substance G;ADRENOSTERONE;Andrenosterone;Reichstein'REICHSTEIN'S 'G';(+)-ADRENOSTERONE;Adrenosterone >REICHSTEIN'S ''G''
CBNumber:
CB1765508
???:
C19H24O3
??? ??:
300.39
MOL ??:
382-45-6.mol

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219-222 °C(lit.)
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300 º (c=1 in chloroform)
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381.62°C (rough estimate)
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1.1381 (rough estimate)
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290 ° (C=0.2, EtOH)
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Sealed in dry,Room Temperature
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optical activity
[α]20/D +300°, c = 1 in chloroform
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98.49mg/L(23.5℃)
Merck
14,176
InChIKey
RZRPTBIGEANTGU-IRIMSJTPSA-N
CAS ??????
382-45-6(CAS DataBase Reference)
NIST
Androst-4-ene-3,11,17-trione(382-45-6)

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WGK ?? 3

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Off-White to Pale Yellow Solid

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Androstenedione is a steroid hormone. It is used to make medicine. Androstenedione is used to increase the production of the hormone testosterone to enhance athletic performance, increase energy, keep red blood cells healthy, enhance recovery and growth from exercise, and increase sexual desire and performance.

benefits

Adrenosterone is sold as a dietary supplement since 2007 as a fat loss and muscle gaining supplement. It is thought to be a competitive selective 11βHSD1 inhibitor, which is responsible for activation of cortisol from cortisone. Thus preventing muscle breakdown, and contributing to a majority of its effects.

Purification Methods

Dissolve adrenosterone i n Me2CO, decolorise it with charcoal, filter, add H2O, Me2CO evaporate and the solid is recrystallised from aqueous EtOH. Also recrystallise it from Et2O or Et2O/pentane and dry it at 110o/0.1mm for 2hours. It can be sublimed under high vacuum. [Reichstein Helv Chim Acta 20 953, 979 1937, Mason et al. J Biol Chem 116 267 1936, Beilstein 7 III 4601.]

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