AC-TRP-3,5-BIS(????????)??????
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AC-TRP-3,5-BIS(????????)?????? ??? ???
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- ?? ??:
- 148451-96-1
- ???:
- AC-TRP-3,5-BIS(????????)??????
- ???(??):
- AC-TRP-3,5-BIS(????????)??????
- ???:
- AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER
- ???(??):
- L732138;L-732,138;AC-TRP-3,5-BIS(TRIFLUOROMETHYL)BENZYL ESTER;N-acetyl-L-tryptophan 3,5-bis*(trifluoromethyl)be;3,5-bis(trifluoromethyl)benzyl N-acetyltryptophan;N-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROM ETHYL)BENZ;3,5-Bis(trifluoromethyl)benzyl acetyl-L-tryptophanate;N-ACETYL-L-TRYPTOPHAN 3,5-BIS(TRIFLUOROMETHYL)-BENZYL ESTER;N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester,L-732,138;L-Tryptophan, N-acetyl-, [3,5-bis(trifluoromethyl)phenyl]methyl ester
- CBNumber:
- CB1721780
- ???:
- C22H18F6N2O3
- ??? ??:
- 472.38
- MOL ??:
- 148451-96-1.mol
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AC-TRP-3,5-BIS(????????)?????? ??
- ???
- 147-148 °C(lit.)
- ?? ?
- 554.1±50.0 °C(Predicted)
- ??
- 1.396±0.06 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Store in freezer, under -20°C
- ???
- Soluble to 100 mM in ethanol and to 100 mM in DMSO
- ?? ?? (pKa)
- 14.63±0.46(Predicted)
- ??? ??
- ??
- ??
- White to off-white
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????(GHS): |
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| ?? ?: |
Warning |
| ??·?? ??: |
| ?? |
??·?? ?? |
?? ?? |
?? |
?? ? |
?? ?? |
P- ?? |
| H302 |
??? ??? |
?? ?? ?? - ?? |
?? 4 |
?? |
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P264, P270, P301+P312, P330, P501 |
| H315 |
??? ??? ??? |
????? ?? ????? |
?? 2 |
?? |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
?? ?? ??? ??? |
?? ? ?? ?? ??? ?? |
?? 2A |
?? |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
?? ???? ??? ? ?? |
?? ???? ?? - 1? ??;???? ?? |
?? 3 |
?? |
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| ??????: |
| P261 |
??·?·??·???·??·...·????? ??? ????. |
| P280 |
????/???/???/?????? ?????. |
| P301+P312 |
??? ???? ??? ????(??)? ??? ????. |
| P302+P352 |
??? ??? ??? ?? ????. |
| P305+P351+P338 |
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????. |
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AC-TRP-3,5-BIS(????????)?????? C??? ??, ??, ??
??
L-732,138 is a Substance P (SP) receptor antagonist.
???? ??
Potent and highly selective competitive tachykinin NK 1 receptor antagonist (IC 50 = 2.3 nM).
AC-TRP-3,5-BIS(????????)?????? ?? ?? ? ???
???
?? ??
AC-TRP-3,5-BIS(????????)?????? ?? ??
???( 54)?? ??
AC-TRP-3,5-BIS(????????)?????? ?? ??:
