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MMP-2 Inhibitor II

MMP-2 Inhibitor II ??? ???
?? ??:
869577-51-5
???:
MMP-2 Inhibitor II
???(??):
MMP-2 Inhibitor II;MMP-2 Inhibitor II - CAS 869577-51-5 - Calbiochem;MMP-2 Inhibitor II (Matrix Metalloproteinase-2 Inhibitor II);N-[4-[4-(oxiran-2-ylmethylsulfonyl)phenoxy]phenyl]methanesulfonamide;N-[4-[4-[(2-oxiranylmethyl)sulfonyl]phenoxy]phenyl]-methanesulfonamide;Methanesulfonamide, N-[4-[4-[(2-oxiranylmethyl)sulfonyl]phenoxy]phenyl]-
CBNumber:
CB13152691
???:
C16H17NO6S2
??? ??:
383.44
MOL ??:
869577-51-5.mol

MMP-2 Inhibitor II ??

?? ?
591.7±60.0 °C(Predicted)
??
1.460±0.06 g/cm3(Predicted)
?? ??
-20C
???
≤200mg/ml in DMSO
??? ??
?? ??
?? ?? (pKa)
8.13±0.10(Predicted)
??
white

??

MMP-2 Inhibitor II C??? ??, ??, ??

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An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 μM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 μM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS.

Biochem/physiol Actions

Secondary TargetMMP-2 (Ki = 45 and 379 μM for MMP-1 and MMP-7, respectively)

MMP-2 Inhibitor II ?? ?? ? ???

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MMP-2 Inhibitor II ?? ??

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