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50909-86-9
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COELENTERAZINE H
???(??):
COEL;CLZ-H;CLZN-H;ENTERAZINE H;Colenterazine H;COELENTERAZINE H;H-coelenterazine;Renilla Luciferin;LUCIFERIN (RENILLA);2-DEOXYCOELENTERAZINE
CBNumber:
CB1304820
???:
C26H21N3O2
??? ??:
407.46
MOL ??:
50909-86-9.mol
MSDS ??:
SDS

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???
>200℃
?? ?
593.5±60.0 °C(Predicted)
??
1.26±0.1 g/cm3(Predicted)
?? ??
-20°C
???
???, ???? ???
?? ?? (pKa)
10.50±0.30(Predicted)
??? ??
??
??? ??
??? ??
??
???
?? ??(λmax)
437nm
???
??? ??? ?????? 1? ?? ??????. DMSO ?? ??? ??? -20°C?? ?? 1?? ?? ??? ? ????.
??? ??? ??
Calcium indicator; assaying luminescent enzyme; measuring luciferase activity; as a substrate for luciferase; screening HIV-1 protease inhibitors; bioluminescence resonance energy transfer (BRET) detection system
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
HS ?? 2933998090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
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P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

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Coelenterazine h, is a derivative of Coelenterazine (C636000), and iis more sensitive to Ca2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca2+ concentrations.

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Coelenterazine is an imidazopyrazinone derivative. It is a substrate for bioluminescence in many luminous marine organisms.

Biochem/physiol Actions

10 times higher luminescence intensity than native coelenterazine.

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