ChemicalBook >?? ???? >PD-L1 inhibitor 1
PD-L1 inhibitor 1
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PD-L1 inhibitor 1 ??
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- 611.4±55.0 °C(Predicted)
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- 1.133±0.06 g/cm3(Predicted)
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- -20°C
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- DMSO(?? 25mg/ml) ?? ???(?? 25mg/ml)? ?????.
- ?? ?? (pKa)
- 16.06±0.46(Predicted)
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- ??? ?? ?????? 1? ?? ??????. DMSO ?? ??? ??? -20°C?? ?? 3?? ?? ??? ? ????.
PD-L1 inhibitor 1 C??? ??, ??, ??
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The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) interaction plays a dominant role in the suppression of T cell responses, especially in a tumor microenvironment, protecting tumor cells from lysis. PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM.PD-L1 inhibitor 1 ?? ?? ? ???
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PD-L1 inhibitor 1 ?? ??
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