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?? ??:: 81732-65-2

???:: ????

???(??):: ????

???:: Bambuterol

???(??):: CS-1238;BAMBUTEROL;BAMBUTEROLE HCL;Bambuterol USP/EP/BP;Bambuterol ((±)-Bambuterol);Bambuterol & Bambuterol Hydrochloride;5-[2-(ter-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate);[3-(Dimethylcarbamoyloxy)-5-[1-hydroxy-2-(tert-butylamino)ethyl]phenyl]N,N-dimethylcarbamate;Bis(dimethylcarbamic acid)5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester;[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate

CBNumber:: CB1298679

???:: C18H29N3O5

??? ??:: 367.45

MOL ??:: 81732-65-2.mol

?? ?? 78

???? ??

?? ?: 500.9±50.0 °C(Predicted)

??: 1.154±0.06 g/cm3(Predicted)

?? ??: Store at -20°C

???: H₂O: ~33 mg/mL, ???

?? ?? (pKa): 13.70±0.20(Predicted)

??? ??: ??

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CAS ??????: 81732-65-2

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WGK ??	3
??	LDLo ipr-mus: 0.3 mg/kg JPETAB 293,896,2000

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Bambuterol is a new once-daily, oral bronchodilator especially useful in the chronic treatment of nocturnal asthma. It is a prodrug slowly converted by hydrolysis in the lung tissue to terbutaline, generating long-acting bronchodilation with comparable side effects.

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ChEBI: A carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthm , it is a prodrug for terbutaline.

???

A poison.

Safety Profile

A poison by intraperitoneal route.When heated to decomposition it emits toxic vapors ofNOx.

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2',5'-Dihydroxyacetophenone Palladium hydroxide ???? ??????

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???	??	???	??	?? ?	??
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???? ?? ??:

????-p-?????? ??? ??????? 4-?????? ??-??????????? ????? Pirbuterol Methyl 4-tert-butylbenzoate 2-(METHYLSULFONYL)ETHANOL BAMBUTEROL HYDROCHLORIDE,BAMBUTEROL HCL,Bambuterol monohydrochloride ,BAMBUTEROL HYDROCHLORIDE, EP STANDARD Orciprenaline 5-(1-Hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol 2-HYDROXY-2-(3,5-DIMETHOXYPHENYL)ETHYLAMINE Bambuterol 4-aminoacetophenone (intermediate of bambuterol hcl) BAMBUTEROL HCL IMP. D (EP): 5-[(1RS)-1-HYDROXYETHYL]-1,3-PHENYLENE BIS(DIMETHYLCARBAMATE) BAMBUTEROL HCL IMP. E (EP): 5-ACETYL-1,3-PHENYLENE BIS-(DIMETHYLCARBAMATE) 3,5-dihydroxy acetophenone (intermediate of bambuterol hcl)

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