SMAD2 Polyclonal Antibody C??? ??, ??, ??

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SMAD2 is an intracellular protein belonging to the Dwarfin (DWA/B)/SMAD family. SMAD2 associates with SMAD4 for translocation to the nucleus. It acts as an intracellular mediator of the TGFβ family of cytokines and activin type 1 receptor (ACVR1C). Hence it regulates multiple cellular processes like cell growth, proliferation, differentiation, and apoptosis and also cooperates with transcription factors to regulate expression of defined genes. Apart from playing an important role in TGFβ1-induced CTGF expression, SMADs also act as markers of epithelial-mesenchymal transition. SMAD2 also acts as an integrator of multiple signals in the regulation of NOS3 expression. It is ubiquitously expressed in most of tissues and may contribute to colorectal, hepatocellular, lung, and breast carcinomas as well as cervical cancer.

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Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	27736	58
Enzo Biochem Inc	Enzo Biochem Inc. 13797054060	Enzoname@qq.com	China	177174	58
Signalway Antibody LLC	025-58868422	info@sabbiotech.com	China	99242	58
huaxingbio	1-4006-909-904 13121892008	huaxingbio@163.com	China	1178	58
Elabscience Biotechnology Co Ltd	400999210	marketing@elabscience.cn	China	14096	58
Suzhou Four A Biotech Biotechnology Co Ltd	51265829739	info@4abio.com	China	11554	58
BIOSWAMP CO LTD	027-85586319 0278558631	bio-swampname@qq.com	China	26725	58
Abnova Corporation	886-28751-1888	sales@abnova.com	China	21427	58
ProteoGenix SAS	33390205470	contact@proteogenix.fr	China	6526	58