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5,6-??????

5,6-??????
5,6-?????? ??? ???
?? ??:
14430-23-0
???:
5,6-??????
???(??):
5,6-??????
???:
5,6-Dimethoxyindole
???(??):
5,6-DIMETHOXY-1H-INDOLE;AKOS JY2083477;5,6-DIMETHOXYINDOLE;5,6-Dimethoxyindole,99%;5,6-Dimethoxyindole 99%;1H-Indole, 5,6-dimethoxy-;5,6-Dimethoxy-1H-indole99%;5,6-Dimethoxy-1H-indole 99%
CBNumber:
CB1129065
???:
C10H11NO2
??? ??:
177.2
MOL ??:
14430-23-0.mol

5,6-?????? ??

???
154-157 °C (lit.)
?? ?
198°C 8mm
??
1.182±0.06 g/cm3(Predicted)
???
198°C/8mm
?? ??
Sealed in dry,Room Temperature
?? ?? (pKa)
16.93±0.30(Predicted)
??? ??
??
??
????
???
?? ???.
?? ??(λmax)
306nm(EtOH)(lit.)
BRN
5683
InChIKey
QODBZRNBPUPLEZ-UHFFFAOYSA-N
CAS ??????
14430-23-0(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
????? 22-24/25
WGK ?? 3
F ?????? 10
?? ?? IRRITANT
HS ?? 29339900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
NFPA 704
1
2 0

5,6-?????? C??? ??, ??, ??

??? ??

Beige powder

??

5,6-Dimethoxyindole is an indole derivative as analgesic antiinflammatory. It was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.

?? ??

5,6-Dimethoxyindole was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.
Reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reaction
Reactant in synthesis of benzyl trimethoxyindoles
Reactant for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitors
Reactant for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitors
Reactant for preparation of tryptophanol derivatives via the Grignard reaction

Synthesis Reference(s)

Journal of the American Chemical Society, 75, p. 5887, 1953 DOI: 10.1021/ja01119a030
Synthesis of 5,6-Dimethoxyindoles and 5,6-Dimethoxyoxindoles. A New Synthesis of Indoles DOI: 10.1021/ja01619a049

5,6-?????? ?? ?? ? ???

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