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Pyrrobutamine

Pyrrobutamine ??? ???
?? ??:
91-82-7
???:
Pyrrobutamine
???(??):
Pyronil;Pyrrobutamide;Pyrrobutamine;1-[γ-(p-Chlorobenzyl)cinnaMyl]pyrrolidine;1-(4-(4-chlorophenyl)-3-phenylbut-2-enyl)pyrrolidine;1-[4-(4-Chlorophenyl)-3-phenyl-2-butenyl]pyrrolidine;1-[3-(4-Chlorobenzyl)-3-phenyl-2-propenyl]pyrrolidine;1-[4-(4-Chlorophenyl)-3-phenyl-2-buten-1-yl]pyrrolidine;1-[(E)-4-(4-chlorophenyl)-3-phenylbut-2-enyl]pyrrolidine;Pyrrolidine, 1-[4-(4-chlorophenyl)-3-phenyl-2-buten-1-yl]-
CBNumber:
CB0928816
???:
C20H22ClN
??? ??:
311.85
MOL ??:
91-82-7.mol

Pyrrobutamine ??

???
48-49°
?? ?
bp0.3 190-195°
??
d25 1.1052
???
1.6000 (estimate)
???
?????? ? ???
?? ?? (pKa)
pKa 8.77(H2O t=25 c=0.002 to 0.01) (Uncertain)
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??
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271.3mg/L(37.5℃)

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Pyrrobutamine C??? ??, ??, ??

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Pyrrobutamine is an intermediate in the synthesis of Pyrrobutamine Hydrochloride (P997800), which is an antihistaminic.

???

Pyronil (Lilly).

Pyrrobutamine ?? ?? ? ???

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Pyrrobutamine ?? ??

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