?????
|
|
????? ??
- ???
- 140-143 °C(lit.)
- ?? ?
- 394.2±25.0 °C(Predicted)
- ??
- 1.368
- ?? ??
- Keep in dark place,Inert atmosphere,Room temperature
- ???
- DMSO(?? ???), ???(?? ???)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 3.75±0.10(Predicted)
- ??
- ???? ?????
- BRN
- 1868205
- CAS ??????
- 88-97-1(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
????? C??? ??, ??, ??
??
Phthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity.?? ??
Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (kobs) as 5.1×10-5sec-1 at pH 1.3-1.8 and 35°C. It undergoes hydrolysis about 105 times faster than benzamide.????? ?? ?? ? ???
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?? ??
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???( 102)?? ??
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PHTHALANILLIC ACID
N-(4-(acetylsulphamoyl)phenyl)phthalamic acid
(S)-(-)-N-(1-PHENYLETHYL)PHTHALAMIC ACID
Phthalylsulfathiazole
N-(4-THIOPHEN-2-YL-THIAZOL-2-YL)-PHTHALAMIC ACID
Ftaxilide
N-Metatolyl phthalamic acid
4'-SULFAMOYLPHTHALANILIC ACID
2-[[(2-CHLOROPHENYL)AMINO]CARBONYL]-BENZOIC ACID
N-(2,5-DIMETHYL-PHENYL)-PHTHALAMIC ACID
2-{[(3-CHLOROPHENYL)AMINO]CARBONYL}-BENZOIC ACID
N,N-BIS[(S)-(-)-1-PHENYLETHYL]PHTHALAMIC ACID,N,N-BIS((S)-1-PHENYLETHYL) PHTHALAMIC ACID
N,N-DIETHYL-PHTHALAMIC ACID ETHYL ESTER
N-(4-METHOXY-PHENYL)-PHTHALAMIC ACID
(R)-(+)-N-(1-PHENYLETHYL)PHTHALAMIC ACID
o-Phthalamic acid