3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT&
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3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& ??
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- 205 °C (dec.)(lit.)
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- Store at -20°C
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- DMF: 0.25 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 1 mg/ml
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- optical activity
- [α]22/D +21.5°, c = 2 in 1 N HCl: ethanol, 1:2
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????? | 22-24/25 | ||
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WGK ?? | 3 |
3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& C??? ??, ??, ??
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3,3'',5-Triiodo-L-thyronine (T3) is a thyroid hormone. It is produced by 5''-monodeiodination of the prohormone thyroxine (T4) in various tissues, including liver and kidney. T3 is an agonist of thyroid hormone receptors TRα and TRβ (Kis = 2.3 nM for both) that modulates diverse biological properties, including metabolism, cardiac function, growth, and redox signaling. It also functions as an inhibitor of L-type amino acid transporter 1 (LAT1), inhibiting LAT1-mediated leucine uptake in HEK293 cells when used at a concentration of 10 μM.3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& ?? ?? ? ???
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3 3' 5-TRIIODO-L-THYRONINE SODIUM SALT& ?? ??
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