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Chevalone C

Chevalone C ??? ???
?? ??:
1318025-77-2
???:
Chevalone C
???(??):
Chevalone C;(2S,4aR,4bR,6aS,12aS,12bR,14aR)-2-(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one;1H,11H-Phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one, 2-(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-, (2S,4aR,4bR,6aS,12aS,12bR,14aR)-
CBNumber:
CB04665926
???:
C28H40O5
??? ??:
456.61
MOL ??:
1318025-77-2.mol

Chevalone C ??

?? ?
541.2±50.0 °C(Predicted)
??
1.15±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
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DMSO? ???
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Chevalone C C??? ??, ??, ??

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Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). Chevalone C inhibits the growth of multidrug-resistant isolates of E. coli, S. aureus, and E. faecium in a disc diffusion assay when used at a concentration of 15 μg/disc. It also induces cell death in HCT116 colorectal carcinoma cells.

Chevalone C ?? ?? ? ???

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Chevalone C ?? ??

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