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Lercanidipine hydrochloride

Lercanidipine hydrochloride ??? ???
?? ??:
132866-11-6
???:
Lercanidipine hydrochloride
???(??):
LERCANIDIPINE HCL;CLAP;mE10;R 75;BCL10;c-E10;CIPER;CarMen;Lercan;LerzaM
CBNumber:
CB0371085
???:
C36H42ClN3O6
??? ??:
648.19
MOL ??:
132866-11-6.mol
MSDS ??:
SDS

Lercanidipine hydrochloride ??

???
175-177°C
?? ??
2-8°C
???
Methanol[soluble in]
???
???? ???
??? ??
??
??
???
Merck
14,5446
InChIKey
WMFYOYKPJLRMJI-UHFFFAOYSA-N
SMILES
C1(C)NC(C)=C(C(OC(C)(C)CN(CCC(C2=CC=CC=C2)C2=CC=CC=C2)C)=O)C(C2=CC=CC([N+]([O-])=O)=C2)C=1C(OC)=O.[H]Cl
CAS ??????
132866-11-6(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T
?? ???? ?? 25
????? 36/37-45
????(UN No.) UN 2811
WGK ?? 3
HS ?? 2933.39.4100
?? LD50 in mice (mg/kg): 83 i.p.; 657 orally (Nardi)
????(GHS): GHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H301 ??? ??? ?? ?? ?? - ?? ?? 3 ?? GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
??????:
P301+P310 ???? ?? ????(??)? ??? ????.
NFPA 704
0
2 0

Lercanidipine hydrochloride C??? ??, ??, ??

??? ??

Pale-Yellow Powder

??

A dihydropyridine calcium channel blocker. Antihypertensive.

???? ??

L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.

Lercanidipine hydrochloride ?? ?? ? ???

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Lercanidipine hydrochloride ?? ??

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Lercanidipine hydrochloride ?? ??:

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