(1R)-(-)-10-Camphorsulfonic acid
|
|
(1R)-(-)-10-Camphorsulfonic acid ??
- ???
- 198 °C (dec.)(lit.)
- ?? ?
- 344.46°C (rough estimate)
- ??
- -22 º (c=20,H2O)
- ??
- 1.2981 (rough estimate)
- ???
- -21.5 ° (C=5, H2O)
- ?? ??
- Store below +30°C.
- ???
- DMSO(?? ???), ???(?? ???), ?(???? ??)
- ?? ?? (pKa)
- 1.17±0.50(Predicted)
- ??? ??
- ??? ??
- ??
- ???? ?? ????
- ??????(pH)
- 1.2-1.4 (20g/l, H2O)
- optical activity
- [α]20/D 21°, c = 2 in H2O
- ???
- ??
- ??
- Hygroscopic
- BRN
- 2809676
- ???
- ????. ???. ???, ????? ???? ????.
- InChIKey
- MIOPJNTWMNEORI-XVKPBYJWSA-N
- CAS ??????
- 35963-20-3(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | C | ||
|---|---|---|---|
| ?? ???? ?? | 34 | ||
| ????? | 26-36/37/39-45-24/25-27 | ||
| ????(UN No.) | UN 3261 8/PG 2 | ||
| WGK ?? | 3 | ||
| F ?????? | 3-10 | ||
| TSCA | Yes | ||
| ?? ?? | 8 | ||
| ???? | III | ||
| HS ?? | 29147090 |
(1R)-(-)-10-Camphorsulfonic acid C??? ??, ??, ??
??? ??
(1R)-(-)-10-Camphorsulfonic acid is a kind of prismatic crystals and its melting point is 193-195 ° C (decompose). It is Insoluble in ether and slightly soluble in glacial acetic acid and ethyl acetate. And it is and moisture in wet air.??
1R)-(-)-10-Camphorsulfonic acid is a chiral derivative of Camphor.It has the following uses:(1)It is also used for the racemization of optical isomers.
(2) It can be applied to the resolution of intermediate or isomer in medicine.
(3) It also could play a role as organic synthesis intermediates and resolving agent.
??
ChEBI: The R enantiomer of camphorsulfonic acid.?? ??
(1R)-(-)-10-Camphorsulfonic acid is an HPLC derivatization reagent for UV/Vis detection. It is mainly employed for the resolution of bases.Purification Methods
It forms prisms from AcOH or EtOAc, and is deliquescent in moist air. Store it in tightly stoppered bottles. The NH4 salt forms needles from H2O [] D ±20.5o (c 5, H2O). [Burgess & Lowry J Chem Soc 127 279 1925, Marsi et al. J Am Chem Soc [ 78 3063 1956.] The RS-acid recrystallises from AcOH. [60g of (±)-acid in 60mL of AcOH at 105o gave 40g of crystals has m 202-203o [Bartlett & Knox Org Synth 45 12 1965.] [Beilstein 11 IV 642.](1R)-(-)-10-Camphorsulfonic acid ?? ?? ? ???
???
?? ??
(1R)-(-)-10-Camphorsulfonic acid ?? ??
???( 624)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 |
sales@ichemie.com | China | 1015 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 |
abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12809 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5868 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 |
nickzhang@hangyubiotech.com | China | 10983 | 58 |
| airuikechemical co., ltd. | +86-18353166132 +86-18353166132 |
sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3692 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29730 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 |
info@dakenam.com | China | 19805 | 58 |
| Shanghai Bojing Chemical Co.,Ltd. | +86-86-02137122233 +8613795318958 |
bj1@bj-chem.com | China | 299 | 55 |