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- ???
- 120-130 °C
- ?? ?
- 579.6±60.0 °C(Predicted)
- ??
- 1.36
- ?? ??
- -20°C
- ???
- DMSO, ???(?? ???)
- ?? ?? (pKa)
- 14.55±0.10(Predicted)
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- CAS ??????
- 101622-51-9(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
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| WGK ?? | 3 | ||
| HS ?? | 29339980 |
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white to off-white solid???? ??
Cyclin-dependent kinase inhibitor that competes for the ATP binding site of the kinase. Selectively inhibits cdc2/cyclin B (IC 50 = 7 μ M), cdk2/cyclin A (IC 50 = 7 μ M), cdk2/cyclin E (IC 50 = 7 μ M), cdk/p35 kinase (IC 50 = 3 μ M)? and ERK1/MAP kinase (IC 50 = 25 μ M). Arrests human fibroblasts in the G1 phase.?? ???
This ATP site-competitive purine derivative (FW = 298.35 g/mol; CAS 101622-51-9), systematically named 6-benzylamino-2-[2-hydroxyethylamino]- 9-methylpurine, is a potent inhibitor of cyclin-dependent kinases, with an IC50 value of 7 μM for both cdk1 and cdk2 and an IC50 value of 3 μM for cdk5, arresting cells in G1. Olomoucine also inhibits cytokinin 7b-glucosyltransferase.???? ?? ?? ? ???
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SU 9516
NU6102
PURVALANOL A
OLOMOUCINE II
2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE
AMINOPURVALANOL A
ARCYRIAFLAVIN A
Roscovitine
SELICICLIB
(S)-ROSCOVITINE
OLOMOUCINE, N9-ISOPROPYL-,N9-ISOPROPYL-OLOMOUCINE
OLOMOUCINE
ISO-OLOMOUCINE,OLOMOUCINE, ISO-
OLOMOUCINE, DIMETHYLAMINO,DIMETHYLAMINO-OLOMOUCINE
OLOMOUCINE (DRY ICE)
N-G-PROPYL OLOMOUCINE
OLOMOUCINE II