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2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE

2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE ??? ???
?? ??:
83012-13-9
???:
2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE
???(??):
BUTTPARK 147\04-11;4-CHLORO-2,8-DI(TRIFLUOROMETHYL)QUINOLINE;4-Chloro-2,8-bis(trifluoromethyl)quinolone;4-CHLORO-2,8-BIS(TRIFLUOROMETHYL)QUINOLINE;2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE;2,8-Bis(trifluoromethyl)-4-chloroquinoline97%;Quinoline, 4-chloro-2,8-bis(trifluoromethyl)-;4-Chloro-2,8-bis(trifluoromethyl)quinoline,97%;4-CHLORO-2 8-BIS(TRIFLUOROMETHYL)QUINOLINE 97%;2,8-Bis(trifluoromethyl)-4-chloroquinoline 97%
CBNumber:
CB0301493
???:
C11H4ClF6N
??? ??:
299.6
MOL ??:
83012-13-9.mol

2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE ??

???
46-48 °C (lit.)
?? ?
148-152 °C(Press: 18 Torr)
??
1.5242 (estimate)
???
>230 °F
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
?? ?? (pKa)
-3.49±0.50(Predicted)
??? ??
??? ??
??
????
CAS ??????
83012-13-9(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-37/39
WGK ?? 3
?? ?? IRRITANT
HS ?? 29334900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE C??? ??, ??, ??

??? ??

beige crystalline powder

?? ??

4-Chloro-2,8-bis(trifluoromethyl)quinolone is the intermediate formed during the synthesis of quinoline derivatives.

2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE ?? ?? ? ???

???

?? ??


2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE ?? ??

???( 108)?? ??
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2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE ?? ??:

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