ChemicalBook >?? ???? >4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione ??? ???

?? ??:: 1533519-84-4

???:: 4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione

???(??):: LES10;Lesinurad INT3;LESINURAD intermdiate;Lesinurad intermediate;4-triazole-5(4H)-thione;4-(4-Cyclopropylnaphthalen-1-yl)-1H-1;1,4-Pentanediamine,N4-(6-methoxy-11-quinolinyl)-;4-(4-Cyclopropyl-1-naphthyl)-1,2,4-triazole-5(4H)-thione;4-(4-Cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol;4-(4-cyclopropyl naphthalene-1-yl)-4 H-1,2,4- triazole-3-thiol

CBNumber:: CB02725589

???:: C15H13N3S

??? ??:: 267.35

MOL ??:: 1533519-84-4.mol

?? ?? 189

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione ??

?? ?: 435.2±38.0 °C(Predicted)

??: 1.41±0.1 g/cm3(Predicted)

?? ??: 2-8°C

?? ?? (pKa): 7.89±0.20(Predicted)

CAS ??????: 1533519-84-4

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione C??? ??, ??, ??

??? ??

Off white powder

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4-(4-Cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione is a reagent used in the discovery of Lesinurad, a HEK293 cell-based inhibitor.

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione ?? ?? ? ???

???

1-???????-4-??????? 1-aMino-4-cyclopropylnaphthalene oxalate N-(4-Cyclopropyl-1-naphthalenyl)-2-formylhydrazinecarbothioamide TERT-BUTYL 4-CYCLOPROPYLNAPHTHALEN-1-YLCARBAMATE 1-??????,4-??????- 4-???-L-??? ????,1-??????-4-????????- 1-??????????? 4-cyclopropylnaphthalen-1-aMine hydrochloride 4-Bromo-1-naphthylamine Cyclopropylmagnesium bromide 1-???????

?? ??

RDEA-594???

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione ?? ??

???( 189)?? ??

???	??	???	??	?? ?	??
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4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione ?? ??:

Lesinurad Impurity B Lesinurad Impurity 5 Sodium Salt Lesinurad Impurity C1 Lesinurad Impurity 2 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro Lesinurad Impurity 4 Lesinurad Impurity J Lesinurad Impurity 10 3-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione Lesinurad Impurity 22 4-cyclopropylnaphthalen-1-aMine hydrochloride Lesinurad Impurity A Methyl 2-(5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate N-(4-Cyclopropyl-1-naphthalenyl)-2-formylhydrazinecarbothioamide Lesinurad Impurity N Lesinurad M4 Metabolite NAPHTHALENE, 1-CYCLOPROPYL-4-ISOTHIOCYANATO- lesinurad int

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