成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

S14161

S14161 ??? ???
?? ??:
883046-50-2
???:
S14161
???(??):
S14161;SAG Analog (LowTox);S14161, Apoptotic agent;8-Ethoxy-2-(4-fluorophenyl)-3-nitro-2H-1-benzopyran;2H-1-Benzopyran, 8-ethoxy-2-(4-fluorophenyl)-3-nitro-
CBNumber:
CB02677978
???:
C17H14FNO4
??? ??:
315.2957632
MOL ??:
883046-50-2.mol
MSDS ??:
SDS

S14161 ??

?? ?
456.2±45.0 °C(Predicted)
??
1.34±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
DMSO: ??? ? ??
??? ??
??
??
???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
NFPA 704
0
1 0

S14161 C??? ??, ??, ??

??

D-Cyclins regulate the cell cycle by acting in a complex with cyclin dependent kinases (CDKs) to promote phosphorylation of the retinoblastoma protein and initiate cellular progression from the G1 to the S phase. Cell cycle deregulation in many cancers often results from altered cyclin D/CDK activity. S14161 is a small molecule inhibitor of cyclins D1-D3 expression that inhibits phosphoinositide 3-kinase activity and arrests cells at the G0/G1 phase in a dose-dependent manner (concentrations tested from 5-10 μM). S14161 induces apoptosis in myeloma and leukemia cell lines (IC50s < 10 μM) but is less toxic to normal hematopoietic cells (IC20 > 25 μM). In a mouse model of leukemia, S14161 delayed tumor growth by up to 90% compared to controls at a dose of 100 mg/kg/day.

??

S14161 is a small-molecule inhibitor of D-cyclin transactivation that displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway.

S14161 ?? ?? ? ???

???

?? ??


S14161 ?? ??

???( 33)?? ??
??? ?? ??? ?? ?? ? ??
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 94657 76
Shanghai Tauto Biotech Co., Ltd. 021-51320588
tauto@tautobiotech.com China 3989 66
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57423 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Shanghai Yingxin laboratory equipment Co., Ltd 021-021-59178156 15300768757
359382369@qq.com China 10674 58

S14161 ?? ??:

Copyright 2019 ? ChemicalBook. All rights reserved