2-Bromo-4-methylpyridine
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2-Bromo-4-methylpyridine ??
- ?? ?
- 87 °C/10 mmHg (lit.)
- ??
- 1.545 g/mL at 25 °C (lit.)
- ???
- n
20/D 1.561(lit.)
- ???
- >230 °F
- ?? ??
- Keep in dark place,Sealed in dry,Room Temperature
- ???
- ? ????????, ??? (?? ???)
- ?? ?? (pKa)
- 1.46±0.10(Predicted)
- ??? ??
- ??
- ??
- ?? ???
- Specific Gravity
- 1.545
- BRN
- 107331
- InChI
- InChI=1S/C6H6BrN/c1-5-2-3-8-6(7)4-5/h2-4H,1H3
- InChIKey
- LSZMVESSGLHDJE-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=CC(C)=C1
- CAS ??????
- 4926-28-7(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi,Xn | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38-20/21/22 | ||
| ????? | 26-36-36/37/39 | ||
| WGK ?? | 3 | ||
| ?? ?? | IRRITANT | ||
| HS ?? | 29339900 |
2-Bromo-4-methylpyridine C??? ??, ??, ??
??? ??
Colorless to orange oily liqui??
2-Bromo-4-methylpyridine may be used:- in the total synthesis of ocular age pigment A2-E (2 equiv of retinal (vitamin A) and 1 equiv of ethanolamine)
- in the preparation of methoxy-2-(2-pyridyl)indoles
- in the preparation of 2-(2′,4′-difluorophenyl)-4-methylpyridine, via a Suzuki coupling reaction with 2,4-difluorophenylboronic acid
?? ??
2-Bromo-4-methylpyridine can be used as an intermediate in organic synthesis and medicinal chemistry, mostly in the structural modification and synthesis of drug molecules. In basic chemistry research, the substance can be used for the synthesis of a series of organic nitrogen ligands containing pyridine units, and has good applications in the basic research of methodology of transition metal catalysis.2-Bromo-4-methylpyridine ?? ?? ? ???
???
2-????-4-?????
????????????
2-???-4-?????-???
γ-???
?????
4-Methylpyridin-2-amine
4-METHYL-PYRIDINE-2-CARBOXYLIC ACID
?? ??
2-Bromo-4-methylpyridine ?? ??
???( 585)?? ??
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2-Bromo-4-methylpyridine ?? ??:
2-???-5-???????? 2,6-??? γ-??? 2,4,6-??? ??
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