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2",3",5"-?????-?????

2
2",3",5"-?????-????? ??? ???
?? ??:
10302-78-0
???:
2",3",5"-?????-?????
???(??):
2",3",5"-?????-?????
???:
2'',3'',5''-Triacetyl -azacytidine
???(??):
Nsc291930;-O-triacetate;Triacetyl azacitidine;Azacitidine Triacetate;Azacitidine Impurity 48;Intermediate of Azacitidine;2'3'5'-triacetyl-5-Azacytosine;2',3',5'-triacetyl-5-Azacytidine;2',3',5'-Tri-O-Acetyl-Azacytidine;2'',3'',5''-Triacetyl -azacytidine
CBNumber:
CB01564248
???:
C14H18N4O8
??? ??:
370.31
MOL ??:
10302-78-0.mol

2",3",5"-?????-????? ??

?? ?
497.3±55.0 °C(Predicted)
??
1.60±0.1 g/cm3(Predicted)
?? ??
Keep in dark place,Inert atmosphere,2-8°C
???
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
??? ??
??? ??
?? ?? (pKa)
3.06±0.20(Predicted)
CAS ??????
10302-78-0
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

2",3",5"-?????-????? C??? ??, ??, ??

??

5-Azacytidine is an inhibitor of DNA methyltransferase, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.

??? ??

White to off-white powder

??

5-Azacytidine is an inhibitor of DNA methyltransferaes, potentially serving to reverse epigenetic changes. It reduces hypermethylation associated with certain diseases, including myelodysplastic syndromes and cancer. 2’,3’,5’-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally without formation of major metabolites in the gastrointestinal tract.[Cayman Chemical]

2",3",5"-?????-????? ?? ?? ? ???

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2",3",5"-?????-????? ?? ??

???( 111)?? ??
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2",3",5"-?????-????? ?? ??:

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