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2-??-5-??????[2.2.1]??

2-??-5-??????[2.2.1]??
2-??-5-??????[2.2.1]?? ??? ???
?? ??:
279-33-4
???:
2-??-5-??????[2.2.1]??
???(??):
2-??-5-??????[2.2.1]??
???:
2-oxa-5-azabicyclo[2.2.1]heptane
???(??):
5-Aza-2-oxabicyclo[2.2.1]heptane;2-oxa-5-azabicyclo[2.2.1]heptane;5-oxa-2-aza-bicyclo[2.2.1]heptane
CBNumber:
CB01562310
???:
C5H9NO
??? ??:
99.13
MOL ??:
279-33-4.mol

2-??-5-??????[2.2.1]?? ??

?? ?
154℃
??
1.074
???
46℃
?? ?? (pKa)
9.12±0.20(Predicted)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2902900000
????(GHS): GHS hazard pictogramsGHS hazard pictograms
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H227 ??? ?? ??? ?? ?? 4 ?? P210, P280, P370+P378, P403+P235,P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 1 ?? GHS hazard pictograms P280, P305+P351+P338, P310
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P210 ?·???·??·????? ????? - ?? ???.
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P310 ?? ????(??)? ??? ????. ???? ?? ????(??)? ??? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.

2-??-5-??????[2.2.1]?? C??? ??, ??, ??

??

2-Oxa-5-azabicyclo[2.2.1]heptane is used as a reactant in the preparation of benzopyranones and pyrimidoisoquinolinones for DNA-dependent protein kinase inhibitory activity.

2-??-5-??????[2.2.1]?? ?? ?? ? ???

???

?? ??

2-??-5-??????[2.2.1]?? ?? ??

???( 39)?? ??
??? ?? ??? ?? ?? ? ??
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2-??-5-??????[2.2.1]?? ?? ??:

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