ChemicalBook >?? ???? >?? ???>??? ?? ?? ???>?? ??>?? ? ?? ??>5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine ??? ???

?? ??:: 22276-95-5

???:: 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

???(??):: 7-BroMo-6-chloro-7-deazapurine;5-Bromo-4-chloro-7H-pyrro...;5-broMo-4-chloro-7H-pyrrolo[2;5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine;4-chloro-5-bromo-7H-pyrrolo[2,3-d]pyrimidine;5-bromo-4-chloro-1H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-4-chloro-;5-bromo-4-chloro-7h-pyrrole [2,3-d] pyrimidine;5-Bromo-4-chloro-7H-pyrrolo[2,3-D]pyrimidine ,98%;JR-13964, 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine, 95%

CBNumber:: CB01075223

???:: C6H3BrClN3

??? ??:: 232.47

MOL ??:: 22276-95-5.mol

?? ?? 202

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine ??

???: 221-225℃

?? ?: 221.0±50.0 °C(Predicted)

??: 2.15±0.1 g/cm3(Predicted)

?? ??: under inert gas (nitrogen or Argon) at 2-8°C

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 9.43±0.20(Predicted)

??: ???

???: ?? ?? ?????.

InChIKey: OXLMTRZWMHIZBY-UHFFFAOYSA-N

CAS ??????: 22276-95-5

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xn
?? ???? ??	22
????(UN No.)	2811
WGK ??	3
?? ??	IRRITANT
?? ??	6.1
????	Ⅲ
HS ??	2933599590

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H301	??? ???	?? ?? ?? - ??	?? 3	??		P264, P270, P301+P310, P321, P330,P405, P501

??????:

P301+P310

???? ?? ????(??)? ??? ????.

NFPA 704

	1
3		0

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine C??? ??, ??, ??

??

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Synthesis

4-chloro-7H-pyrrolo[2,3-d]pyrimidine (30 g/0.02 mol) was dissolved in 75 mL of chloroform, followed by added 3.5 g (0.02 mol) of N-bromosuccinamide. The resulting mixture was refluxed for 1 h. After cooling to room temperature, the precipitate was removed by filtration and dried under reduced pressure to afford 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine.

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine ?? ?? ? ???

???

N-????????? ????? ???? ???????????? ???????? ?????? ?? ?? ?????????

?? ??

4-???-7H-???[2,3-d]????-5-?????? JAK3-IN-6

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine ?? ??

???( 202)?? ??

???	??	???	??	?? ?	??
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
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Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	1227	58
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Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine ?? ??:

2-????? ???? ???? ????????? ?????????? ?? 5-BROMO-7-NITRO-1H-INDAZOLE 5-BROMO-1H-PYRROLO[2 , 3-B]PYRIDIN-2(3H)-ONE 5-Bromo-7-nitroindoline 4-Amino-7H-pyrrolo[2,3-d]pyrimidine 2-Amino-4-chloropyrrolo[2,3-d]pyrimidine 2,4-DICHLORO-5H-PYRROLO[3,2-D]PYRIMIDINE 4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine Pyrrolo[2,3-d]pyrimidin-4-ol N4-Benzoylcytosine 4-CHLORO-7-TOSYL-7H-PYRROLO[2,3-D]PYRIMIDINE 4-Aminopyrazolo[3,4-d]pyrimidine Chlorobromoisocyanurate 5-bromo-7H-pyrrolo[2,3-d]pyrimidine

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