セフカペン 化學(xué)特性,用途語(yǔ),生産方法
効能
抗生物質(zhì), 細(xì)胞壁合成阻害薬
使用
Cefcapene is a metabolite of Cefcapene Pivoxil (C242550). Antibacterial, orally absorbed cephalosporin that is used in the treatment of bacterial infections.
定義
ChEBI: Cefcapene is a cephalosporin compound having (carbamoyloxy)methyl and N-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino side-groups. It is used (generally as the corresponnding pivaloyloxymethyl ester prodrug) as an oral antibacterial. It has a role as an antibacterial drug. It is a cephalosporin, a carboxylic acid, a carbamate ester, an enamide, a member of 1,3-thiazoles and a secondary carboxamide.
抗菌性
A semisynthetic cephalosporin formulated for oral administration
as the prodrug ester, cefcapene pivoxil. Activity and
uses are similar to those of cefditoren.
Available in Japan.
薬物動(dòng)態(tài)學(xué)
Cefcapene is a semisynthetic third-generation cephalosporin with antibacterial activity. Cefcapene binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
6436055
セフカペン 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品